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Ro (antigen) : ウィキペディア英語版
Anti-SSA/Ro autoantibodies

Anti-SSA autoantibodies (Anti-Sjögren’s-syndrome-related antigen A, also called anti-Ro, or the combination anti-SSA/Ro or anti Ro/SSA autoantibodies) are anti-nuclear autoantibodies that are associated with many autoimmune diseases, such as systemic lupus erythematosus (SLE), SS/SLE overlap syndrome, subacute cutaneous LE (SCLE), neonatal lupus and primary biliary cirrhosis. Also, they are often present in Sjögren's syndrome.

Presence of Anti-SSA/Ro in pregnant women with SLE is associated with an increased risk of neonatal lupus erythematosus in the child.〔James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. Page 160. ISBN 0-7216-2921-0.〕
Ro protein binds to Y RNA
==Epidemiology==
Approximately only 0.1 to 0.5 percent of the general population has the antibody.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Anti-SSA/Ro autoantibodies」の詳細全文を読む



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